Ebook Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy Molecular Mechanisms and Clinical Applications (Cancer Drug Discovery and Development)
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Cisplatin, the first member of the family of platinum-containing chemotherapeutic agents, was discovered by Barnett Rosenberg in 1965 and approved by the FDA for marketing in 1978. After 30 years of use in the clinic, cisplatin remains a central element of many treatment regimens. Cisplatin is still an irreplaceable component of a regimen that produces high cure rates in even advanced nonseminomatous germ-cell cancers, and is widely used in the treatment of ovarian cancers and other gynecologic cancers, head and neck, and numerous other tumor types. The development of carboplatin has reduced some of the adverse events associated with cisplatin treatment, and the introduction of the DACH platinum compound oxaliplatin has broadened the spectrum of activity of the platinums to include gastro-intestinal cancers, especially colorectal cancer. The clinical importance of this family of drugs continues to drive investigation into how these drugs work and how to improve their efficacy and reduce their toxicity. The papers in this volume were presented in Verona, Italy, during the tenth International Symposium on Platinum Coordination Compounds in Cancer Chemotherapy. The symposium was jointly organized by the Department of Oncology of the Mater Salutis Hospital – Azienda Sanitaria Locale 21 of the Veneto Region – and by the Department of Medicine and Public Health, Section of Pharmacology, the University of Verona. They reflect the vitality of this field and the increasing use of new molecular and cell biologic, genetic, and biochemical tools to identify approaches to further improve their use. Dr. Nieper's Revolution in Technology Medicine and Society "Revolution in Technik Medizin Gesellschaft" Hans A. Nieper ISBN 3-925188-00-2 English: "Dr. Nieper's Revolution in Technology Medicine and Society ... Use of Chemotherapy plus a Monoclonal Antibody against ... Original Article. Use of Chemotherapy plus a Monoclonal Antibody against HER2 for Metastatic Breast Cancer That Overexpresses HER2. Dennis J. Slamon M.D. Ph.D ... News - Morningside RDR Staff; Published Online: Tuesday Dec 20 2016. Apellis Pharmaceuticals announced that their orphan drug APL-2 for the treatment of paroxysmal nocturnal ... Intel - Stony Brook University HIGH SCHOOL STUDENTS PROJECT TITLES STONY BROOK FACULTY ADVISORS; Eleni Aneziris Ward Melville HS E. Setauket NY Intel semi-finalist: Effects of Predictability on ... Applications : BioTek Applications. The following resources are available to illustrate product specific capabilities and common applications for BioTek microplate instrumentation. Resolve a DOI Name Type or paste a DOI name into the text box. Click Go. Your browser will take you to a Web page (URL) associated with that DOI name. Send questions or comments to doi ... Chemical causes (toxics / biocides) Inicial UFRGS 0 points: 1 point: 2 points: Activity (muscle tone) no movement "floppy" tone: arms and legs flexed with little movement: active spontaneous movement: Pulse What the Experts Say About Colloidal Silver! What the experts say about colloidal silver and other silver-based antimicrobials... [While the FDA uses their legal prerogative to assert that colloidal silver has ... Heavy metals - Wikipedia This table shows the number of heavy metal criteria met by each metal out of the ten criteria listed in this section i.e. two based on density three on atomic ... Antibiotic-Resistant Bugs in the 21st Century A Clinical ... Perspective. Antibiotic-Resistant Bugs in the 21st Century A Clinical Super-Challenge. Cesar A. Arias M.D. Ph.D. and Barbara E. Murray M.D.
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